Consequences
from most medical interfering trials have disastrous to explain a beneficial
consequence of vitamin C supplementation on the chief or secondary anticipation
of cardiovascular disease. In the Women's Antioxidant Cardiovascular Study, a
less vital expectancy trial involving 8,171 women elderly 40 years or older
with a the past of cardiovascular disease, supplementation with 500 mg/day
vitamin C for a mean of 9.4 years showed no overall effect on cardiovascular
actions .likewise, vitamin C supplementation (500 mg/day) for a denote
follow-up of 8 years had no effect on main cardiovascular events in male
physicians enrolled in the Physicians' Health Study II .Other clinical trials
have normally examined the effects on cardiovascular disease of supplements
combining vitamin C with other antioxidants, such as vitamin E and
beta-carotene, making it more difficult to isolate the possible contribution of
vitamin C. The SU.VI.MAX study examined the belongings of a combination of
vitamin C (120 mg/day), vitamin E (30 mg/day), beta-carotene (6 mg/day),
selenium (100 mcg/day), and zinc (20 mg/day) in 13,017 French adults from the
general inhabitants .After a center take notes time of 7.5 years, the combined
supplements had no result on ischemic cardiovascular disease in either men or
women. In the Women's Angiographic Vitamin and Estrogen (WAVE) study, involving
423 postmenopausal women with at least one coronary stenos is of 15%–75%,
supplements of 500 mg vitamin C plus 400 IU vitamin E twice per day not only
provided no cardiovascular benefit, but significantly increased all-cause humanity
compare with placebo .
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