All
through the 1970s, studies by Cameron, Campbell, and Pauling discretionary that
high-dose vitamin C has useful property on quality of life and endurance time
in patients with incurable cancer .However, some consequent studies—including a
randomized, double-blind, placebo-controlled experimental trial by Mortal and
colleagues at the Mayo Clinic did not bear these findings. In the Mortal study,
patients with advanced correctional cancer who received 10 g/day vitamin C
fared no better than those getting a placebo. The authors of a 2003 review
assessing the effects of vitamin C in patients with superior cancer completed
that vitamin C confers no significant mortality benefit Emerging study suggests
that the route of vitamin C administration (intravenous vs. oral) could make
clear the conflicting findings Most intervention trials, together with the one
conducted by Mortal and colleagues, used only oral direction, whereas Cameron
and colleagues used a grouping of oral and intravenous (IV) administration.
Oral administration of vitamin C, even of very large doses, can raise plasma
vitamin C concentrations to a most of only 220 micro mole/L, whereas IV
administration can make plasma concentration as high as 26,000 micro mole/L
Concentrations of this magnitude are selectively toxicity to tumor cells in
nitro .Research in mice suggests that pharmacological doses of IV vitamin C
might show undertake in treating otherwise difficult-to-treat tumors .A high
attention of vitamin C may act as a pro-oxidant and generate hydrogen remove
the color that has selective toxicity toward cancer cells .Based on these
findings and a few case reports of patients with advanced cancers who had
remarkably long endurance times following administration of high-dose IV
vitamin C, some researchers support reassessment of the use of high-dose IV
vitamin C as a drug to treat cancer .As discussed below, it is uncertain
whether supplemental vitamin C and other antioxidants might interact with
chemotherapy and/or energy .Therefore, individuals undergoing these actions
should consult with their oncologist earlier to taking vitamin C or other
antioxidant supplements, particularly in high doses .
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